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Imaging the high-affinity state of the dopamine D(2) receptor in vivo: Fact or fiction?

Positron Emission Tomography (PET) has been used for more than three decades to image and quantify dopamine D(2) receptors (D(2)R) in vivo with antagonist radioligands but in the recent years agonist radioligands have also been employed. In vitro competition studies have demonstrated that agonists b...

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Bibliographic Details
Main Authors: Skinbjerg, Mette, Sibley, David R., Javitch, Jonathan A., Abi-Dargham, Anissa
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610415/
https://ncbi.nlm.nih.gov/pubmed/21945484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.09.008
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