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Non-allosteric enzyme switches possess larger effector-induced changes in thermodynamic stability than their non-switch analogs

The ability to regulate cellular protein activity offers a broad range of biotechnological and biomedical applications. Such protein regulation can be achieved by modulating the specific protein activity or through processes that regulate the amount of protein in the cell. We have previously demonst...

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Detalhes bibliográficos
Main Authors: Choi, Jay H, San, Angela, Ostermeier, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610053/
https://ncbi.nlm.nih.gov/pubmed/23400970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2234
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