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Non-allosteric enzyme switches possess larger effector-induced changes in thermodynamic stability than their non-switch analogs

The ability to regulate cellular protein activity offers a broad range of biotechnological and biomedical applications. Such protein regulation can be achieved by modulating the specific protein activity or through processes that regulate the amount of protein in the cell. We have previously demonst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Jay H, San, Angela, Ostermeier, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610053/
https://ncbi.nlm.nih.gov/pubmed/23400970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2234
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