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Simvastatin attenuates stroke-induced splenic atrophy and lung susceptibility to spontaneous bacterial infection in mice

BACKGROUND AND PURPOSE: Statins are widely used in the primary and secondary prevention of ischemic stroke, but their effects on stroke-induced immunodeppression and post-stroke infections are elusive. We investigated effects of simvastatin treatment on stroke-induced splenic atrophy and lung suscep...

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Bibliographische Detailangaben
Hauptverfasser: Jin, Rong, Zhu, Xiaolei, Liu, Lin, Nanda, Anil, Granger, D Neil, Li, Guohong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609888/
https://ncbi.nlm.nih.gov/pubmed/23391769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.000633
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