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Phosphatidylinositol-3-kinase (PI3K) gamma plays a central role in blood-brain barrier dysfunction in acute experimental stroke

BACKGROUND AND PURPOSE: Phosphoinositide 3-kinase (PI3K) gamma is linked to inflammation and oxidative stress. This study was conducted to investigate the role of the PI3Kgamma in the blood-brain barrier (BBB) dysfunction and brain damage induced by focal cerebral ischemia/reperfusion. METHODS: Wild...

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Autori principali: Jin, Rong, Song, Zifang, Yu, Shiyong, Piazza, Abigail, Nanda, Anil, Penninger, Josef M, Granger, D Neil, Li, Guohong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129812/
https://ncbi.nlm.nih.gov/pubmed/21546487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.601369
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