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SeqEntropy: Genome-Wide Assessment of Repeats for Short Read Sequencing
BACKGROUND: Recent studies on genome assembly from short-read sequencing data reported the limitation of this technology to reconstruct the entire genome even at very high depth coverage. We investigated the limitation from the perspective of information theory to evaluate the effect of repeats on s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609794/ https://ncbi.nlm.nih.gov/pubmed/23544073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059484 |
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