SeqEntropy: Genome-Wide Assessment of Repeats for Short Read Sequencing

BACKGROUND: Recent studies on genome assembly from short-read sequencing data reported the limitation of this technology to reconstruct the entire genome even at very high depth coverage. We investigated the limitation from the perspective of information theory to evaluate the effect of repeats on s...

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Bibliografiska uppgifter
Huvudupphovsmän: Chu, Hsueh-Ting, Hsiao, William WL., Tsao, Theresa TH., Hsu, D. Frank, Chen, Chaur-Chin, Lee, Sheng-An, Kao, Cheng-Yan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609794/
https://ncbi.nlm.nih.gov/pubmed/23544073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059484
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