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Trace Amine-Associated Receptor 1 (TAAR(1)) is Activated by Amiodarone Metabolites

Amiodarone (Cordarone, Wyeth-Ayerst Pharmaceuticals) is a clinically available drug used to treat a wide variety of cardiac arrhythmias. We report here the synthesis and characterization of a panel of potential amiodarone metabolites that have significant structural similarity to thyroid hormone and...

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Bibliografiske detaljer
Main Authors: Snead, Aaron N., Miyakawa, Motonori, Tan, Edwin S., Scanlan, Thomas S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609712/
https://ncbi.nlm.nih.gov/pubmed/18752950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.08.013
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