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DC matured by inflammation induce CD86-dependent priming of naïve CD8(+) T cells in the absence of their cognate peptide antigen
DC licensed by the interaction between pathogen products and pattern recognition receptors can activate naïve T cells to undergo antigen-dependent proliferation and cytokine production. In contrast, DC induced to mature by trans-acting inflammatory stimuli are believed to only be capable of supporti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609600/ https://ncbi.nlm.nih.gov/pubmed/19917700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901330 |
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