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Alzheimer Aβ peptide interactions with lipid membranes: Fibrils, oligomers and polymorphic amyloid channels

Fibrillar aggregates of misfolded amyloid proteins are involved in a variety of diseases such as Alzheimer disease (AD), type 2 diabetes, Parkinson, Huntington and prion-related diseases. In the case of AD amyloid β (Aβ) peptides, the toxicity of amyloid oligomers and larger fibrillar aggregates is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tofoleanu, Florentina, Buchete, Nicolae-Viorel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609060/
https://ncbi.nlm.nih.gov/pubmed/22874669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.21022
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