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BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses

Histone acetylation regulates activation and repression of multiple inflammatory genes known to play critical roles in chronic inflammatory diseases. However, proteins responsible for translating the histone acetylation code into an orchestrated pro-inflammatory cytokine response remain poorly chara...

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Bibliografische gegevens
Hoofdauteurs: Belkina, Anna C., Nikolajczyk, Barbara S., Denis, Gerald V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608815/
https://ncbi.nlm.nih.gov/pubmed/23420887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202838
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