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The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis

Bromodomain-containing transcriptional regulators represent new epigenetic targets in different hematologic malignancies. However, bromodomain-mediated mechanisms that couple histone acetylation to transcription in lymphopoiesis and govern mature lymphocyte mitogenesis are poorly understood. Brd2, a...

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Détails bibliographiques
Auteurs principaux: Belkina, Anna C., Blanton, Wanda P., Nikolajczyk, Barbara S., Denis, Gerald V.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923082/
https://ncbi.nlm.nih.gov/pubmed/24319289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1112588
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