Bile Salt Export Pump is Dysregulated with Altered Farnesoid X Receptor Isoform Expression in Patients with Hepatocellular Carcinoma

As a canalicular bile acid effluxer, bile salt export pump (BSEP) plays a vital role in maintaining bile acid homeostasis. BSEP deficiency leads to severe cholestasis and hepatocellular carcinoma (HCC) in young children. Regardless of the etiology, chronic inflammation is the common pathological pro...

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Detalhes bibliográficos
Main Authors: Chen, Yuan, Song, Xiulong, Valanejad, Leila, Vasilenko, Alexander, More, Vijay, Qiu, Xi, Chen, Weikang, Lai, Yurong, Slitt, Angela, Stoner, Matthew, Yan, Bingfang, Deng, Ruitang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608797/
https://ncbi.nlm.nih.gov/pubmed/23213087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26187
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