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Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pump

Z-Guggulsterone is a major ingredient in the Indian traditional hypolipidemic remedy guggul. A study in mice has established that its hypolipidemic effect involves the farnesoid X receptor (FXR), presumably by acting as an antagonist of this receptor. It is generally assumed that the antagonism lead...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Dongfang, Yang, Jian, Shi, Deshi, Xiao, Da, Chen, Yi-Tzai, Black, Chris, Deng, Ruitang, Yan, Bingfang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276476/
https://ncbi.nlm.nih.gov/pubmed/22246918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M014688
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