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Liver receptor homolog 1 transcriptionally regulates human bile salt export pump expression
The metabolic conversion of cholesterol into bile acids in liver is initiated by the rate-limiting cholesterol 7α-hydroxylase (CYP7A1), whereas the bile salt export pump (BSEP) is responsible for the canalicular secretion of bile acids. Liver receptor homolog 1 (LRH-1) is a key transcriptional facto...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311441/ https://ncbi.nlm.nih.gov/pubmed/18270374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M700417-JLR200 |
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