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Inhibitors of PI(4,5)P(2) Synthesis Reveal Dynamic Regulation of IgE Receptor Signaling by Phosphoinositides in RBL Mast Cells

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is a versatile phospholipid that participates in many membrane-associated signaling processes. PI(4,5)P(2) production at the plasma membrane (PM) depends on levels of its precursor, phosphatidylinositol 4-phosphate (PI4P), synthesized principally b...

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Detalhes bibliográficos
Main Authors: Santos, Marcela de Souza, Naal, Rose Mary Zumstein Georgetto, Baird, Barbara, Holowka, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608441/
https://ncbi.nlm.nih.gov/pubmed/23313938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.082834
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