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Activation of Cdc42 is necessary for sustained oscillations of Ca(2+) and PIP(2) stimulated by antigen in RBL mast cells
Antigen stimulation of mast cells via FcεRI, the high-affinity receptor for IgE, triggers a signaling cascade that requires Ca(2+) mobilization for exocytosis of secretory granules during the allergic response. To characterize the role of Rho GTPases in FcεRI signaling, we utilized a mutant RBL cell...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133723/ https://ncbi.nlm.nih.gov/pubmed/24996924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148862 |
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