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TRIVALENT LIGANDS WITH RIGID DNA SPACERS REVEAL STRUCTURAL REQUIREMENTS FOR IgE RECEPTOR SIGNALING IN RBL MAST CELLS
Antigen-mediated crosslinking of immunoglobulin E (IgE) bound to its receptor, FcεRI, stimulates degranulation, phospholipid metabolism, and cytokine production in mast cells and basophils to initiate inflammatory and allergic responses. Previous studies suggested that spatial organization of the cl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519021/ https://ncbi.nlm.nih.gov/pubmed/18041817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb7001472 |
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