Extinction of phosphoenolpyruvate carboxykinase gene expression is associated with loss of a specific chromatin-binding protein from a far upstream domain.

We have analyzed the chromatin structure of the phosphoenolpyruvate carboxykinase (PEPCK) gene in hepatoma x fibroblast hybrids with different extinction phenotypes. These hybrids included a karyotypically complete hybrid in which all liver gene activity was extinguished, a microcell hybrid that con...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Ip, Y T, Fournier, R E, Chalkley, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2355923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.7.3782-3787.1990
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