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Extinction of phosphoenolpyruvate carboxykinase gene expression is associated with loss of a specific chromatin-binding protein from a far upstream domain.

We have analyzed the chromatin structure of the phosphoenolpyruvate carboxykinase (PEPCK) gene in hepatoma x fibroblast hybrids with different extinction phenotypes. These hybrids included a karyotypically complete hybrid in which all liver gene activity was extinguished, a microcell hybrid that con...

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Ip, Y T, Fournier, R E, Chalkley, R
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360833/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2355923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.7.3782-3787.1990
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