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Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene.

We have previously generated microphthalmic mice lacking lens fiber cells by targeting the expression of the diphtheria toxin A (DT-A) gene in transgenic mice with regulatory sequences associated with the mouse gamma 2-crystallin gene. Because of the extreme toxicity of DT to animal cells and the po...

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Autores principales: Breitman, M L, Rombola, H, Maxwell, I H, Klintworth, G K, Bernstein, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC360817/
https://ncbi.nlm.nih.gov/pubmed/2300048
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