Immunoglobulin D switching can occur through homologous recombination in human B cells.

Prototypical class switching in mouse and human immunoglobulin heavy chains occurs through recombination of tandem blocks of short repeats located 5' to each heavy chain constant region (CH) except C delta. Deletion of C mu in immunoglobulin D (IgD)-secreting murine plasmacytomas occurs illegit...

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Библиографические подробности
Главные авторы: White, M B, Word, C J, Humphries, C G, Blattner, F R, Tucker, P W
Формат: Artigo
Язык:Inglês
Опубликовано: 1990
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC360814/
https://ncbi.nlm.nih.gov/pubmed/2113175
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