A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation

BACKGROUND: DNA methylation and demethylation are important epigenetic regulatory mechanisms in eukaryotic cells and, so far, only partially understood. We exploit the minimalistic biological ciliate system to understand the crosstalk between DNA modification and chromatin structure. In the macronuc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bulic, Aneta, Postberg, Jan, Fischer, Andreas, Jönsson, Franziska, Reuter, Günter, Lipps, Hans J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608066/
https://ncbi.nlm.nih.gov/pubmed/23497475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-5
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