A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation

BACKGROUND: DNA methylation and demethylation are important epigenetic regulatory mechanisms in eukaryotic cells and, so far, only partially understood. We exploit the minimalistic biological ciliate system to understand the crosstalk between DNA modification and chromatin structure. In the macronuc...

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Autores principales: Bulic, Aneta, Postberg, Jan, Fischer, Andreas, Jönsson, Franziska, Reuter, Günter, Lipps, Hans J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608066/
https://ncbi.nlm.nih.gov/pubmed/23497475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-5
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