A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation

BACKGROUND: DNA methylation and demethylation are important epigenetic regulatory mechanisms in eukaryotic cells and, so far, only partially understood. We exploit the minimalistic biological ciliate system to understand the crosstalk between DNA modification and chromatin structure. In the macronuc...

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Bibliografiska uppgifter
Huvudupphovsmän: Bulic, Aneta, Postberg, Jan, Fischer, Andreas, Jönsson, Franziska, Reuter, Günter, Lipps, Hans J
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608066/
https://ncbi.nlm.nih.gov/pubmed/23497475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-5
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