Cell division promotes efficient retrotransposition in a stable L1 reporter cell line

BACKGROUND: Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) complex, which must enter the nucleus before retrotransposition can proceed. Thus...

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Bibliographische Detailangaben
Hauptverfasser: Xie, Yi, Mates, Lajos, Ivics, Zoltán, Izsvák, Zsuzsanna, Martin, Sandra L, An, Wenfeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Short Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607998/
https://ncbi.nlm.nih.gov/pubmed/23497436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-4-10
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