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The Ancient mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on Transposon Ends

Hsmar1, one of the two subfamilies of mariner transposons in humans, is an ancient element that entered the primate genome lineage ∼50 million years ago. Although Hsmar1 elements are inactive due to mutational damage, one particular copy of the transposase gene has apparently been under selection. T...

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Main Authors: Miskey, Csaba, Papp, Balázs, Mátés, Lajos, Sinzelle, Ludivine, Keller, Heiko, Izsvák, Zsuzsanna, Ivics, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900042/
https://ncbi.nlm.nih.gov/pubmed/17403897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02027-06
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