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Regulation of DNA transposition by CpG methylation and chromatin structure in human cells

BACKGROUND: The activity of transposable elements can be regulated by different means. DNA CpG methylation is known to decrease or inhibit transpositional activity of diverse transposons. However, very surprisingly, it was previously shown that CpG methylation of the Sleeping Beauty (SB) transposon...

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Detalhes bibliográficos
Main Authors: Jursch, Tobias, Miskey, Csaba, Izsvák, Zsuzsanna, Ivics, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680223/
https://ncbi.nlm.nih.gov/pubmed/23676100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-4-15
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