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Regulation of DNA transposition by CpG methylation and chromatin structure in human cells

BACKGROUND: The activity of transposable elements can be regulated by different means. DNA CpG methylation is known to decrease or inhibit transpositional activity of diverse transposons. However, very surprisingly, it was previously shown that CpG methylation of the Sleeping Beauty (SB) transposon...

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Bibliographische Detailangaben
Hauptverfasser: Jursch, Tobias, Miskey, Csaba, Izsvák, Zsuzsanna, Ivics, Zoltán
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680223/
https://ncbi.nlm.nih.gov/pubmed/23676100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-4-15
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