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Frog Prince transposon-based RNAi vectors mediate efficient gene knockdown in human cells

We have developed a stable RNA interference (RNAi) delivery system that is based on the Frog Prince transposable element. This plasmid-based vector system combines the gene silencing capabilities of H1 polymerase III promoter-driven short hairpin RNAs (shRNA) with the advantages of stable and effici...

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Autors principals: Kaufman, Christopher D, Izsvák, Zsuzsanna, Katzer, Andrea, Ivics, Zoltán
Format: Artigo
Idioma:Inglês
Publicat: Library Publishing Media 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737204/
https://ncbi.nlm.nih.gov/pubmed/19771210
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