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Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function

Cardiac troponin T (cTnT) has a highly acidic extended N-terminus, the physiological role of which remains poorly understood. To decipher the physiological role of this unique region, we deleted specific regions within the N-terminus of mouse cTnT (McTnT) to create McTnT(1-44Δ) and McTnT(45-74Δ) pro...

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Bibliographische Detailangaben
Hauptverfasser: Mamidi, Ranganath, Mallampalli, Sri Lakshmi, Wieczorek, David F, Chandra, Murali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607867/
https://ncbi.nlm.nih.gov/pubmed/23207592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.243394
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