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Assessing the Consequences of Denoising Marker-Based Metagenomic Data

Early marker-based metagenomic studies were performed without properly accounting for the effects of noise (sequencing errors, PCR single-base errors, and PCR chimeras). Denoising algorithms have been developed, but they were validated using data derived from mock communities, in which the true sequ...

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Autori principali: Gaspar, John M., Thomas, W. Kelley
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607570/
https://ncbi.nlm.nih.gov/pubmed/23536909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060458
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