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Denoising PCR-amplified metagenome data
BACKGROUND: PCR amplification and high-throughput sequencing theoretically enable the characterization of the finest-scale diversity in natural microbial and viral populations, but each of these methods introduces random errors that are difficult to distinguish from genuine biological diversity. Sev...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563472/ https://ncbi.nlm.nih.gov/pubmed/23113967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-283 |
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