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Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data

BACKGROUND: The accuracy of microbial community surveys based on marker-gene and metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA sequences not truly present in the sample. Contaminants come from various sources, including reagents. Appropriate laboratory practices can redu...

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Bibliografiska uppgifter
I publikationen:Microbiome
Huvudupphovsmän: Davis, Nicole M., Proctor, Diana M., Holmes, Susan P., Relman, David A., Callahan, Benjamin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298009/
https://ncbi.nlm.nih.gov/pubmed/30558668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-018-0605-2
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