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FlowClus: efficiently filtering and denoising pyrosequenced amplicons

BACKGROUND: Reducing the effects of sequencing errors and PCR artifacts has emerged as an essential component in amplicon-based metagenomic studies. Denoising algorithms have been designed that can reduce error rates in mock community data, but they change the sequence data in a manner that can be i...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Gaspar, John M, Thomas, W Kelley
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380255/
https://ncbi.nlm.nih.gov/pubmed/25885646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0532-1
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