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Inhibitors of bacterial tubulin target bacterial membranes in vivo

FtsZ is a homolog of eukaryotic tubulin that is widely conserved among bacteria and coordinates the assembly of the cell division machinery. FtsZ plays a central role in cell replication and is a target of interest for antibiotic development. Several FtsZ inhibitors have been reported. We characteri...

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Detalhes bibliográficos
Main Authors: Foss, Marie H., Eun, Ye-Jin, Grove, Charles I., Pauw, Daniel A., Sorto, Nohemy A., Rensvold, Jarred W., Pagliarini, David J., Shaw, Jared T., Weibel, Douglas B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607388/
https://ncbi.nlm.nih.gov/pubmed/23539337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD20127E
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