ATM-dependent DNA damage checkpoint functions regulate gene expression in human fibroblasts

The relationships between profiles of global gene expression and DNA damage checkpoint functions were studied in cells from patients with ataxia telangiectasia (AT). Three telomerase-expressing AT fibroblast lines displayed the expected hypersensitivity to ionizing radiation (IR) and defects in DNA...

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Huvudupphovsmän: Zhou, Tong, Chou, Jeff, Zhou, Yingchun, Simpson, Dennis A., Cao, Feng, Bushel, Pierre R., Paules, Richard S., Kaufmann, William K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607384/
https://ncbi.nlm.nih.gov/pubmed/17699107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-0104
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