Genome-wide Analysis Reveals Extensive Functional Interaction between DNA Replication Initiation and Transcription in the Genome of Trypanosoma brucei

Identification of replication initiation sites, termed origins, is a crucial step in understanding genome transmission in any organism. Transcription of the Trypanosoma brucei genome is highly unusual, with each chromosome comprising a few discrete transcription units. To understand how DNA replicat...

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Main Authors: Tiengwe, Calvin, Marcello, Lucio, Farr, Helen, Dickens, Nicholas, Kelly, Steven, Swiderski, Michal, Vaughan, Diane, Gull, Keith, Barry, J. David, Bell, Stephen D., McCulloch, Richard
Format: Artigo
Language:Inglês
Published: Cell Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607257/
https://ncbi.nlm.nih.gov/pubmed/22840408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.06.007
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