Fluorescent Mu Selective Opioid Ligands from a Mixture Based Cyclic Peptide Library

A positional scanning cyclic peptide library was generated using a penta-peptide thioester scaffold. Glycine was fixed at position R(1). Diaminopropionic acid was fixed at position R(3), with its γ-amino attaching to an anthraniloyl group. Positions R(2) and R(4) contained 36 L- and D- amino acids a...

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Hauptverfasser: Li, Yangmei, Dooley, Colette T., Misler, Jaime A., Debevec, Ginamarie, Giulianotti, Marc A., Cazares, Margaret E., Maida, Laura, Houghten, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607207/
https://ncbi.nlm.nih.gov/pubmed/23110623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co300110t
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