Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis

Sporadic and familiar amyotrophic lateral sclerosis (ALS) cases presented lower cholinergic activity than in healthy individuals in their still preserved spinal motoneurons (MNs) suggesting that cholinergic reduction might occur before MN death. To unravel how and when cholinergic function is compro...

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Bibliografske podrobnosti
Main Authors: Casas, Caty, Herrando-Grabulosa, Mireia, Manzano, Raquel, Mancuso, Renzo, Osta, Rosario, Navarro, Xavier
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607155/
https://ncbi.nlm.nih.gov/pubmed/23531559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.104
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