Therapeutic Role of Neuregulin 1 Type III in SOD1-Linked Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating motoneuron (Mn) disease without effective cure currently available. Death of MNs in ALS is preceded by failure of neuromuscular junctions and axonal retraction. Neuregulin 1 (NRG1) is a neurotrophic factor highly expressed in MNs and neuromuscular...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Mòdol-Caballero, Guillem, García-Lareu, Belén, Verdés, Sergi, Ariza, Lorena, Sánchez-Brualla, Irene, Brocard, Frédéric, Bosch, Assumpció, Navarro, Xavier, Herrando-Grabulosa, Mireia
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609630/
https://ncbi.nlm.nih.gov/pubmed/31965551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00811-7
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