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Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis
Sporadic and familiar amyotrophic lateral sclerosis (ALS) cases presented lower cholinergic activity than in healthy individuals in their still preserved spinal motoneurons (MNs) suggesting that cholinergic reduction might occur before MN death. To unravel how and when cholinergic function is compro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607155/ https://ncbi.nlm.nih.gov/pubmed/23531559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.104 |
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