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Lipidome analysis reveals antifungal polyphenol curcumin affects membrane lipid homeostasis

This study shows that antifungal curcumin (CUR), significantly depletes ergosterol levels in Candida albicans. CUR while displaying synergy with fluconazole (FLC) lowers ergosterol. However, CUR alone at its synergistic concentration (lower than MIC(50)), could not affect ergosterol contents. For de...

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書目詳細資料
Main Authors: Sharma, Monika, Dhamgaye, Sanjiveeni, Singh, Ashutosh, Prasad, Rajendra
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607078/
https://ncbi.nlm.nih.gov/pubmed/22201946
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