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Lipidome analysis reveals antifungal polyphenol curcumin affects membrane lipid homeostasis

This study shows that antifungal curcumin (CUR), significantly depletes ergosterol levels in Candida albicans. CUR while displaying synergy with fluconazole (FLC) lowers ergosterol. However, CUR alone at its synergistic concentration (lower than MIC(50)), could not affect ergosterol contents. For de...

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Detalhes bibliográficos
Main Authors: Sharma, Monika, Dhamgaye, Sanjiveeni, Singh, Ashutosh, Prasad, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607078/
https://ncbi.nlm.nih.gov/pubmed/22201946
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