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Serotonin spillover onto the axon initial segment of motoneurons induces central fatigue by inhibiting action potential initiation

Motor fatigue induced by physical activity is an everyday experience characterized by a decreased capacity to generate motor force. Factors in both muscles and the central nervous system are involved. The central component of fatigue modulates the ability of motoneurons to activate muscle adequately...

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Autors principals: Cotel, Florence, Exley, Richard, Cragg, Stephanie J., Perrier, Jean-François
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607056/
https://ncbi.nlm.nih.gov/pubmed/23487756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216150110
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