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Serotonin spillover onto the axon initial segment of motoneurons induces central fatigue by inhibiting action potential initiation

Motor fatigue induced by physical activity is an everyday experience characterized by a decreased capacity to generate motor force. Factors in both muscles and the central nervous system are involved. The central component of fatigue modulates the ability of motoneurons to activate muscle adequately...

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Detalles Bibliográficos
Main Authors: Cotel, Florence, Exley, Richard, Cragg, Stephanie J., Perrier, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607056/
https://ncbi.nlm.nih.gov/pubmed/23487756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216150110
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