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Facile Functionalization of Polyesters through Thiol-yne Chemistry for the Design of Degradable, Cell–Penetrating and Gene Delivery Dual–Functional Agents

Synthesis of polyesters bearing pendant amine groups with controlled molecular weights and narrow molecular weight distributions was achieved through ring-opening polymerization of 5-(4-(prop-2-yn-1-yloxy)benzyl)-1,3-dioxolane-2,4-dione, an O-carboxyanhydride derived from tyrosine, followed by thiol...

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Autors principals: Zhang, Zhonghai, Yin, Lichen, Xu, Yunxiang, Tong, Rong, Lu, Yanbing, Ren, Jie, Cheng, Jianjun
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606898/
https://ncbi.nlm.nih.gov/pubmed/23098261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301333w
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