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Synthesis of water-soluble poly(α-hydroxy acids) from living ring-opening polymerization of O-benzyl-L-serine carboxyanhydrides

O-benzyl-L-serine carboxyanhydrides were synthesized via diazotization of O-benzyl-L-serine with sodium nitrite in aqueous sulfuric acid solution followed by cyclization of the resulting serine-based α-hydroxy acid with phosgene. Degradable, water-soluble poly(α-hydroxy acids) bearing pendant hydrox...

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Main Authors: Lu, Yanbing, Yin, Lichen, Zhang, Yanfeng, Zhonghai, Zhang, Xu, Yunxiang, Tong, Rong, Cheng, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555137/
https://ncbi.nlm.nih.gov/pubmed/23359651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mz200165c
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