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Click Nucleophilic Conjugate Additions to Activated Alkynes: Exploring Thiol-yne, Amino-yne, and Hydroxyl-yne Reactions from (Bio)Organic to Polymer Chemistry

[Image: see text] The 1,4-conjugate addition reaction between activated alkynes or acetylenic Michael acceptors and nucleophiles (i.e., the nucleophilic Michael reaction) is a historically useful organic transformation. Despite its general utility, the efficiency and outcomes can vary widely and are...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Worch, Joshua C., Stubbs, Connor J., Price, Matthew J., Dove, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227514/
https://ncbi.nlm.nih.gov/pubmed/33764739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.0c01076
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