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Novel approaches to inhibitor design for the p110β PI 3-kinase
Phosphoinositide 3-kinases (PI 3-kinases) are essential regulators of cellular proliferation, survival, metabolism and motility that are frequently dysregulated in human disease. The design of inhibitors to target the PI 3-kinase/mTOR pathway is a major area of investigation by both academic laborat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606591/ https://ncbi.nlm.nih.gov/pubmed/23411347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.12.004 |
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