Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6∊-FCR3 of the Plasmodium falciparum VAR2CSA protein

The VAR2CSA protein has been closely associated with pregnancy-associated malaria and is recognized as the main adhesin exposed on the surface of Plasmodium falciparum-infected erythrocytes. Chondroitin sulfate A was identified as the main host receptor in the placenta. Single-domain heavy-chain cam...

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Bibliographic Details
Main Authors: Vuchelen, Anneleen, Pardon, Els, Steyaert, Jan, Gamain, Benoît, Loris, Remy, van Nuland, Nico A. J., Ramboarina, Stéphanie
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2013
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606572/
https://ncbi.nlm.nih.gov/pubmed/23519802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113001917
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